Search
Full bibliography 1,272 resources
-
Background:Lipedema, a chronic condition affecting 11% of women, causes abnormal fat buildup in the lower limbs, leading to disproportionate body...
-
BACKGROUNDLipedema is a chronic disorder characterized by disproportionate accumulation of subcutaneous fat, most commonly affecting the extremities,...
-
Lipedema is a chronic, predominantly female disorder characterized by disproportionate regional expansion of subcutaneous adipose tissue, pain, tenderness and easy bruising. Although adipocyte hypertrophy, altered progenitor-cell behavior, microvascular dysfunction, extracellular-matrix remodeling, immune-cell alterations and variable lymphatic abnormalities have been reported, their causal and temporal relationships remain unresolved. Here, we propose that these findings may represent interacting manifestations of dysregulation within an adipovascular unit (AVU) rather than independent pathological processes.
-
Are you newly diagnosed with lipedema, a painful adipose tissue disorder? Maybe you have had the condition for years and are looking for ideas for self-care from a holistic perspective.In this book you will learn:Treatment goals for lipedema / lipoedemaTips for reducing pain and inflammationHow to boost your lymphatic systemIf you are looking for a research-packed guide to caring for lipedema, read this book!Praise for Lipedema Treatment Guide:Steven Dean, DO, FACP, RPVI, Professor of Clinical Internal Medicine, Ohio State University Wexner Medical Center calls the Lipedema Treatment Guide "incredibly well-written and informative" and has added it to his patient lipedema handout.Jacqui Beutel teaches Decongestive Lymphatic Therapy courses in Australia and New Zealand and gives copies of the Lipedema Treatment Guide to her students.
-
Software engineering plays a key role in developing high-quality healthcare systems, particularly in Precision Medicine, where advanced systems are required to tailor clinical interventions based on individual genetic, environmental, and lifestyle factors. Therefore, it is necessary to rethink software engineering methods to address the significant challenges in healthcare systems, especially in system design, complex data analysis, traceability, and AI explainability. This paper presents the MATIIGEN project, which aims to address these challenges. MATIIGEN introduces an intelligent system for automated DNA variant interpretation. The project combines Model-Driven Software Engineering (MDSE) principles with Explainable Artificial Intelligence (XAI) to support the transition of genomic tools from laboratory validation environments (TRL4) to operational clinical settings (TRL6). MDSE provides the structural and methodological basis for building robust, traceable, and interoperable software systems, and XAI provides mechanisms to make the system’s outputs more transparent and understandable to clinicians. The applicability of MATIIGEN platform is demonstrated through a historically overlooked chronic disease: Lipedema. By focusing on a condition that is under-researched in clinical settings, we can demonstrate that the MATTIGEN platform can generate insights in areas of medicine where data is scarce and complex. Our work demonstrates that adopting MDSE principles provides a systematic methodology for transforming multifaceted clinical data into actionable medical insights and establishes a scalable architecture for high-quality, software-intensive systems in the healthcare domain.
-
An evidence-based guide to current understanding of lipedema, its causes and possible treatments, addressing what is known through human studies, what is unknown and needs investigating, and what is likely to emerge. Lipedema (or lipoedema) is a chronic lymphatic disorder in which abnormal levels of fat build up disproportionately in certain areas of the body, most commonly the hips, bottom and legs. Almost exclusively affecting women, who may seek help for years only to be met with ongoing anti-fat stereotyping, its significant life-changing impact has only recently been recognized, clinically and in terms of research funding. Even though research is now accelerating, there is still much left to be discovered. This book brings together the current knowns, unknowns and conjectures as a comprehensive resource for researchers, clinicians and patients seeking a roadmap to potentially improving the lives of up to 17 million women in the US and 350 million worldwide.
-
Lipedema is a chronic and progressive disorder, a primary lipotrophy characterized by abnormal fat deposition, primarily in the buttocks and legs bilaterally. It is symmetrical and disproportionate. It is estimated to affect 10 to 18% of women in Europe and approximately 12.3% of the Brazilian female population.
Explore
Topic
- Genetics (21)
- Guidelines and Consensus (49)
- LF Funded (73)
- Lipedema (1,082)
- Open Access (468)
- Original studies and data (497)
- Patient journey (39)
- Personal management (diet, excercise, nutrition) (54)
- Review (432)
- Therapeutics (93)
Resource type
- Blog Post (5)
- Book (34)
- Book Section (43)
- Conference Paper (15)
- Document (5)
- Journal Article (1,111)
- Magazine Article (4)
- Newspaper Article (1)
- Patent (1)
- Preprint (8)
- Presentation (2)
- Report (18)
- Thesis (8)
- Web Page (17)
Publication year
-
Between 1900 and 1999
(74)
- Between 1910 and 1919 (2)
-
Between 1930 and 1939
(1)
- 1936 (1)
-
Between 1940 and 1949
(2)
- 1940 (2)
- Between 1950 and 1959 (3)
- Between 1960 and 1969 (7)
- Between 1970 and 1979 (6)
- Between 1980 and 1989 (26)
- Between 1990 and 1999 (27)
-
Between 2000 and 2026
(1,181)
- Between 2000 and 2009 (113)
- Between 2010 and 2019 (283)
- Between 2020 and 2026 (785)
- Unknown (17)
Publication
- Open Access (468)